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Gene and Bernie
Millen opened Vital Life Center in 1993.
Can Alpha Lipoic Acid
and Acetyl L Carnitine
Reverse Aging?
Could two nutritional supplements, alpha lipoic acid and acetyl L carnitine really reverse aging? Just maybe.
Picture this scene from an old movie: the elderly scientist, working late in the lab, takes a sip of potion from a bubbling flask and undergoes a miraculous transformation as his body regains its youthful look and vigor.
Science fiction? Maybe not…that’s pretty much what happened to elderly laboratory rats when they were fed two dietary supplements in a recent landmark study conducted by researchers Dr. Bruce Ames and his colleagues from U.C. Berkeley.
Dr. Ames is no newcomer to genetic research. Damaged genes have been his business for half a century. He has published more than 450 articles and is one of the most quoted scientists on the planet.
Ames said with a twinkle in his eye,
"With the two supplements together, these old rats got up and did the Macarena. The brain looks better, they are full of energy… everything we looked at looks more like a young animal."
Co researcher, Tory M. Hagen was also enthusiastic. "The animals fed the supplements seemed to have much more vigor and are much more active. We also see a reversal in loss of memory. That is a dual-track improvement that is significant and unique."
"We significantly reversed the decline in overall activity typical of aged rats to what you see in a middle-aged to young adult rat 7 to 10 months of age," Hagen said. "This is equivalent to making a 75- to 80-year-old person act middle-aged."
For many years Ames and Hagen have been extremely interested the body’s mitochondria and its role in the aging process. Mitochondria are tiny structures inside cells that act like furnaces, manufacturing most of the energy that is used by the body.
The byproduct of this process is oxidation, which causes the formation of free radicals. These free radicals hurtle through our body bombarding our cells and DNA. When free radicals are on the rampage they take building blocks from normal cells and cause those cells to break down, wounding cell membranes and damaging DNA codes within the cell’s nucleus.
The result is aging and disease.
Dr. Hagen explained, "With aging, we see so many different things that are occurring to mitochondria that then lead to consequences in the cell. If you tune up mitochondria you may have a means of at least delaying the onset of a number of age-related problems that we encounter, or we can in some ways, hopefully, reverse what has already taken place."
Over the last few months, scientific interest in alpha lipoic acid (ALA) and acetyl L-carnitine (ALC), the two supplements used in the studies, has exploded and a large number of studies are now under way with humans.
Ames and his researchers are also studying the role of alpha lipoic acid and acetyl L carnitine have in healing heart disease. They theorize that these supplements can improve circulation in cardiovascular patients by relaxing blood vessels, which could reduce the risk of heart attack or stroke.
“I don’t want over hype it” says Ames. “We have to wait for the results of human trials.” But Dr. Ames isn’t waiting. He is taking a dose of ALA and ALC twice a day.
It could take years for these clinical studies to be completed, analyzed and debated by the medical community. In the meantime I've joined Dr. Ames by adding ALA and ALC to my daily vitamin regimen.
It's going to be great fun doing the Macarena. I never did learn how to dance when I was a kid.
Gene
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